erm i havent ridden a VFR.
from what i can gather it has a bit more mid range and a little less top end than the cbr.
mine is an NC23 which is the older of the cbrs there is a NC29 which is basically a different bike with ram air etc.
any post 1988 bike is restricted to 112mph i think the same for NC30's and all the other 400's
cbr is in some ppls opinion harder to ride, but as with all the 400's you need to rev them to get the best from them which can be annoying when commuting and its pishing down.
Handling is good if a little soft for bigger ppl and the brakes are like running into a skip.
im not that fast and it keeps me outta trouble.
comfort is pretty good.
you pay a bit more for a VFR, which is a shame as you can pay silly money for cbr's/vfrs, due to the demand for them. before getting this i went and saw alot of snotters. (i paid £1500 from a dealer, with 19k kms on the clock and is completely unmolested even got the standard can on it still workin on that tho

)
the build quality is good and i have had mine for a year and the only thing i have done to it is put tyres on it and replace a fuel pump.
getting servicing is a little tricky as my local h***a place wont touch it with a barge pole but spare arnt too bad as i have a local h***a parts dealer or use David Silver. Even tho they are getting for 17yrs old they still look good and have the cool sound of gear driven cams and are pretty much unburstable.
Mines in a few bits at present as i remove all the crap from it and get the wheels powder coated.
best source of info is
http://www.400greybike.co.uk/